Director of cell line generation cambridge ma jobs in the Biotech, R&D, Science category in Quincy, Massachusetts

Seeking expert knowledge of assay design and execution specifically for cell based assays, biochemical assays, and histological tests as well as a documented history of effective leadership in a drug discovery environment to lead a small scientific team focused on identifying and evaluating gene expressed proteins or peptides acting as renal biomarkers. PhD relevant field and at least 4 years simi...
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Major developer of novel renal therapeutics seeks 3+ years experience and strong working knowledge of in vivo pharmacology techniques to: * Prepare test compounds * Handle and dose mice * Collect blood and tissue samples for PK and PD biomarker analysis * Establish PK-PD relationships from in vivo assays * Generate human dose predictions for clinical development * Assess the mechanism of action an...
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Seeking Ph.D. or M.D. and 10+ years in pre-clinical drug discovery and development for autoimmune, inflammation or respiratory therapeutic target entities including the development of in vivo, in vitro and ex vivo evaluation models. Shall: * Participate in selection of specific protein & antibody entities as novel targets or drug leads for therapeutic consideration and develop research strategy. *...
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Seeking 3+ years experience developing topical dosage forms such as gels, creams, ointments, lotions, and novel delivery methods. Shall * Conduct preformulation analysis physical and chemical characteristics of the drug and dispersed system including solubility, particle size distribution, surface area, polymorphism, surface tension, and rheology. * Analyze stability and release by visual evaluati...
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Our very well funded, Cambridge, MA based client has science that has the potential to make radical improvements towards human life. If you are seeking to join a company that is very well funded, lead by the very best and brightest, with science stemming from one of the worlds leading labs you have to consider this opportunity. It simply doesn’t get better than this. Sought is a Cell Biologist to ...
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Senior Scientist A leading global Biotech organization is currently recruiting for Sr. Scientist for an interim contract position based in Cambridge, MA. This is a three month contract a generous hourly rate plus overtime. This position is interviewing immediately and can start as soon as possible. Primary responsibilities will focus on the design, synthesis and characterization of novel small mol...
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We are seeking a dynamic thought leader in oncology to develop pre-clinical biomarker strategies derived from clinical data analysis. You will provide scientific and strategic leadership to support oncology molecules in all phases of development. Shall: * Oversee the development of biomarker strategies and ensure successful execution of drug-diagnostic development * Leverage your expertise to driv...
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Seeking experience developing methods for characterization of protein drug candidates, hands on development experience with Liquid chromatography - Mass Spectrometry, two dimensional Gel Electrophoresis, and track record contributing to BLA and IND filings to lead group of 4 scientists supporting process development and final product comparability evaluations for vaccine developer and manufacturer...
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Seeking a seasoned scientific professional who is proficient with all facets of downstream protein manufacturing from pilot to production scale and who is ready to transition into hands on leadership role Requires 4+ years experience developing purification processes for proteins, enzymes, PEGylated proteins, antibodies, or peptides to be scaled up and transferred from development to clinical and ...
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Provide strategic leadership for teams focused on the development of personalized medicine based on the discovery of molecular biomarkers. Utilizing patient derived data from genomic and molecular analyses you will develop strategies to drive oncology therapeutics through the clinic Shall: * Work with clinicians and laboratories to develop novel biomarkers, research tools and study designs derived...
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Seeking extensive clinical development experience to help guide discovery strategies and focus pre-clinical resources and efforts most effectively for big pharma research & development activities. Shall work closely with heads of multiple therapeutic areas and drug discovery units to drive clinical-to-preclinical backward collaboration in an effort to more effectively select targets and entities a...
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Seeking PhD and 2+ years experience in formulating transdermal drug delivery technologies and devices. Must be familiar with: * Preformulation studies of the physical and chemical nature of transdermal drug products * Mix studies of complex pharmaceutical solutions, dispersions, and blends. * Equipment relating to mixing, coating, and packaging of transdermal products * Scale-up, tech transfer, an...
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Seeking a scientific leader to oversee the development of preclinical models of inflammatory diseases to support clinical development collaborations, based on the pathophysiology of disease and the mechanism of action of drugs. Shall: * Prepare, initiate, and manage all preclinical research studies * Establish collaborations with pharmaceutical and academic organizations * Manage a team of up to 1...
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Scientist– Target Biology Ra Pharmaceuticals is an early-stage biotechnology company developing highly modified peptides as novel therapeutics. Ra's approach merges in vitro selection technologies with synthetic biology to construct and screen extremely large and diverse macromolecule libraries. Founded in 2008, Ra has strong venture support and is located in the Kendall Square area of Cambridge, ...
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Job Summary: Sanofi is a global heath care company fully committed to developing novel, safe and effective medicines both through internal efforts and external partnerships. The Scouting and Partnering (S&P) group within the Strategy, External Innovation and Science Policy unit plays a critical role in identifying new partnering opportunities for all therapeutic area units in the company. The scou...
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A global healthcare leader, Novartis has one of the most exciting product pipelines in the industry today. A pipeline of innovative medicines brought to life by diverse, talented, performance driven people. All of which makes us one of the most rewarding employers in our field. We have an immediate opening in the Analytical Sciences group for a highly motivated and experienced analytical scientist...
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Virology II/Discovery Research is looking to fill one scientist level position in the Technologies Projects group who will design, develop and evaluate vaccines as well as immunotherapeutic products for immunization of humans against infectious diseases. These positions will involve planning, conducting and evaluating the utility of a variety of delivery systems and immunotherapeutic proteins usin...
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Job Title: Clinical Trial Head Position Description Accountable for all aspects of assigned OTM clinical trials (Phase I/II) including leading Clinical Trial Team(s) (CTT). Number of clinical trials depends on the workload and complexity of the individual trials. Responsible for program level activities as assigned. Position Responsibilities Lead the clinical protocol development process in collab...
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The Target ID and Validation Group plays a central role in Sanofi Oncology preclinical drug development. The group provides preclinical support for the identification and validation of novel therapeutic targets. About the position: The successful candidate will lead his/her own lab and manage several other labheads primarily responsible for identifying and validating oncology novel targets for bot...
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Continuing meeting the Virology Dept. current and future goals and very aggressive timelines in multiple projects (RepliVax-HIV project funded by a grant from the Gates Foundation, Dengue Next Generation, other new projects/targets that are being discussed, remaining tasks during licencing of RepliVax-Rabies and RepliVax-TBE vaccines, as well as development of general novel methods of manufactirin...
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We seek an experienced bioinformatics scientist / computational biologist to work with therapeutics groups across the sanofi families of companies in Boston. As an part of scientific teams identifying both targets and patient selection biomarkers, you will Develop analysis and quality control pipelines for a variety of Next Generation Sequencing (NGS) applications such as DNA-seq, ChIP-seq, and RN...
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Our Discovery Research group has a position for a Head of CNS Systems Biology. The qualified individual will have a record of accomplishment in pharmaceutical discovery, exemplified by advancement of compounds through the discovery process as well as publications in peer-reviewed journals and of presentations at national and/or international meetings. This position requires a deep scientific under...
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FORMA Therapeutics, Inc. is currently seeking to recruit highly motivated, talented, computational chemists for our laboratories in Watertown, MA. These positions require individuals with an exceptional grasp of state of the art computational techniques and extensive experience in the application of computational science to drug discovery programs from lead generation to lead optimization includin...
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Job details Auto req ID 29422BR School/Unit Harvard Medical School Sub-Unit - Location USA - MA - Boston Job Function Research Department Microbiology and Immunobiology Salary Grade 056 Union 00 - Non Union, Exempt or Temporary Duties & Responsibilities Position open for a PhD-level Researcher at Harvard Medical School (HMS) to study how cytokine signals controls transcriptional activity in cells ...
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There's quite a distance between wondering and knowing. And for patients waiting for answers to important health questions, it's a road they want to travel as quickly as possible. At Quest Diagnostics Incorporated, we understand urgency. But more than speed, we focus our energies on accuracy. Currently, we have an opportunity available for an Associate Genetics Director at our Worcester, MA locati...
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